Connect Python to MS SQL Server To connect Microsoft SQL Server to Python running on Unix or Linux, use pyodbc with the SQL Server ODBC Driver or ODBC-ODBC Bridge (OOB). Connect Python to Oracle® To connect Oracle® to Python, use pyodbc with the Oracle® ODBC Driver. Connect Python to MongoDB To connect MongoDB to Python, use pyodbc with the MongoDB ODBC Driver. Connect Python to DB2 To connect DB2