R. M. Mitchell, BS, W. M. Freeman, PhD, W. T. Randazzo, BS, H. E. Stephens, MA, J. L. Beard, PhD, Z. Simmons, MD and J. R. Connor, PhD From the Departments of Neurosurgery (R.M.M., W.T.R., J.R.C.), Pharmacology (W.M.F.), and Neurology (H.E.S., Z.S.), George M. Leader Family Laboratory, Pennsylvania State University College of Medicine/Milton S. Hershey Medical Center, Hershey; and Department