Cache::Memcached::Fast uses Compress::Zlib by default to use compression. It's bit slow on high traffic environment. I got a Compress::Zlib as a bottleneck in our web application. In this case, you can use Compress::LZ4 for better performance. I'm using this as following form: use Cache::Memcached::Fast; use Compress::LZ4; my $memcache = Cache::Memcached::Fast->new(+{ %{config->cache}, utf8 => 1,