Sir Isaac Newton was pretty sure he was a smart cookie. I mean, after inventing calculus and a theory of gravity, he should be clever enough to do some financial investing, right? Anyway, long story short, he lost $4,600,000 (in today's dollars) in the nationwide speculation frenzy known as the South Sea Bubble of 1720. As Mr. Newton later said: “I can calculate the motion of heavenly bodies, but