Review Open access Published: 31 May 2011 Microarrays, deep sequencing and the true measure of the transcriptome John H Malone1 & Brian Oliver1 BMC Biology volume 9, Article number: 34 (2011) Cite this article Microarrays first made the analysis of the transcriptome possible, and have produced much important information. Today, however, researchers are increasingly turning to direct high-throughpu

Research article Open access Published: 06 June 2011 RNA-seq: technical variability and sampling Lauren M McIntyre1, Kenneth K Lopiano2, Alison M Morse1, Victor Amin1, Ann L Oberg3, Linda J Young2 & …Sergey V Nuzhdin4 Show authors BMC Genomics volume 12, Article number: 293 (2011) Cite this article BackgroundRNA-seq is revolutionizing the way we study transcriptomes. mRNA can be surveyed without p

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Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles Aravind Subramanian, Pablo Tamayo, Vamsi K. Mootha, Sayan Mukherjee, Benjamin L. Ebert, Michael A. Gillette, Amanda Paulovich, Scott L. Pomeroy, Todd R. Golub, Eric S. Lander, and Jill P. Mesirov aBroad Institute of Massachusetts Institute of Technology and Harvard, 320 Charles Street, Cambrid