GSEA
Overview Gene Set Enrichment Analysis (GSEA) is a computational method that determines whether an a priori defined set of genes shows statistically significant, concordant differences between two biological states (e.g. phenotypes). Download the GSEA software and additional resources to analyze, annotate and interpret enrichment results. Explore the Molecular Signatures Database (MSigDB), a collec
Home | www.broadinstitute.org/software/scripture
What is Scripture? Scripture is a method for transcriptome reconstruction that relies solely on RNA-Seq reads and an assembled genome to build a transcriptome ab initio. The statistical methods to estimate read coverage significance are also applicable to other sequencing data. Scripture also has modules for ChIP-Seq peak calling. Download Software The Scripture software is an executable java jar
Sneak Preview: The Spirit of GATK 3.0 | GATK | Blog
Poster Teaser: The Features of GATK 3.0 By Geraldine_VdAuwera Alright, the next release is going to be version 3.0. So what's in it?? We'll have a full overview ready for you in the next few days. In the meantime, if you're at AGBT-2014 working on your tan (lucky devil), one way to find out is to go see Mauricio Carneiro's poster during the Thursday afternoon poster session, and ask him all about
ALLPATHS-LG | High quality genome assembly from low cost data
We are pleased to announce the release of DISCOVAR de novo, our new assembler that is suitable suitable for large genomes up to human size. DISCOVAR de novo, uses the same cheap data that the original DISCOVAR release does: 250 base paired-end PCR-free Illumina reads. No other libraries are required. For more information please visit the DISCOVAR blog, or check out the online demo.
GATK
Genome Analysis Toolkit Variant Discovery in High-Throughput Sequencing Data Need Help? Search our documentation Community Forum Hi, How can we help? Developed in the Data Sciences Platform at the Broad Institute, the toolkit offers a wide variety of tools with a primary focus on variant discovery and genotyping. Its powerful processing engine and high-performance computing features make it capabl
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