You are here: Home / ESXi / How to Enable Support for Nested 64bit & Hyper-V VMs in vSphere 5 With the release of vSphere 5, one of the most sought out feature from VMware is the ability to run nested 64bit and Hyper-V guest virtual machines in a virtual ESXi instance. Previous to this, only 32bit virtual machines were supported as the VT-x/AMD-V Hardware Virtualization CPU instructions could not