PugSQL is a simple Python interface for using parameterized SQL, in files, with any SQLAlchemy-supported database. import pugsql # Create a module of database functions from a set of sql files on disk. queries = pugsql.module('resources/sql') # Point the module at your database. queries.connect('sqlite:///foo.db') # Invoke parameterized queries, receive dicts! user = queries.find_user(user_id=42)