About Quip compresses next-generation sequencing data in the FASTQ and SAM/BAM formats with extreme prejudice. It is lightweight, dependency-free, and open source. Learn More Read the paper Compression of next-generation sequencing reads aided by highly efficient de novo assembly Daniel C. Jones; Walter L. Ruzzo; Xinxia Peng; Michael G. Katze — Nucleic Acids Research 2012; doi: 10.1093/nar/gks754