Update: Check github.com/steida/este, the ES6 React Flux webpack gulp om-like isomorphic immutable k̶i̶t̶c̶h̶e̶n̶s̶i̶n̶k̶ t̶w̶e̶e̶t̶y̶b̶i̶r̶d̶s̶ dev stack. Future now. For view aka user interface, use React.js.For routing, use github.com/rackt/react-router, or Este.js, or anything else even onhashchange event can work. It’s up to you.For module loading, forget about AMD and use CommonJS. You want