Fact Sheet MEDLINE® MEDLINE is the U.S. National Library of Medicine® (NLM) premier bibliographic database that contains more than 24 million references to journal articles in life sciences with a concentration on biomedicine. A distinctive feature of MEDLINE is that the records are indexed with NLM Medical Subject Headings (MeSH®). MEDLINE is the online counterpart to MEDLARS® (MEDical Literature