Selective neuronal damage and Wisconsin Card Sorting Test performance in atherosclerotic occlusive disease of the major cerebral artery Hiroshi Yamauchi1, Ryuichi Nishii2, Tatsuya Higashi2, Shinya Kagawa2, Hidenao Fukuyama11Human Brain Research Center, Kyoto University Graduate School of Medicine, Kyoto, Japan2Research Institute, Shiga Medical Center, Moriyama, JapanCorrespondence to Dr Hiroshi Ya

Cerebral amyloid angiopathy related inflammation: three case reports and a review Kong Khi Chung1, Neil E Anderson1, David Hutchinson1, Beth Synek2, P Alan Barber1,31Department of Neurology, Auckland Hospital, Auckland, New Zealand2Department of Forensic Pathology, Auckland Hospital, Auckland, New Zealand3Faculty of Medicine and Health Sciences, University of Auckland, Auckland, New ZealandCorresp

Dysexecutive versus amnesic phenotypes of very mild Alzheimer's disease are associated with distinct clinical, genetic and cortical thinning characteristics Bradford C Dickerson1,2,3,4, David A Wolk5,6,7, the Alzheimer's Disease Neuroimaging Initiative1Frontotemporal Dementia Unit, Boston, Massachusetts, USA2Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston

W K Tang1, Y K Chen1,2, J Y Lu1, Winnie C W Chu3, V C T Mok2, Gabor S Ungvari1, K S Wong21Department of Psychiatry, Chinese University of Hong Kong, Hong Kong SAR, China2Department of Medicine and Therapeutics, Chinese University of Hong Kong, Hong Kong SAR, China3Department of Diagnostic Radiology and Organ Imaging, Chinese University of Hong Kong, Hong Kong SAR, ChinaCorrespondence to W K Tang,

PATH56 MRI correlates of vascular cognitive impairment: contribution of microbleeds, white matter changes and infarcts in a large hospital-based cross-sectional study S Gregoire, L Cipolotti, N Sokolovsky, M M Brown, T A Yousry, D J Werring, H R Jaeger, K Smith, K Oaksford, G SchefflerUCL Institute of Neurology, London, UKCorrespondence to s.gregoire{at}ion.ucl.ac.uk Background The mechanisms unde

B Ghosh1,2,3, J B Rowe1,2,3, R H S Carpenter1,2,3, A J Calder1,2,3, P V Peers1,2,3, A D Lawrence1,2,3, J R Hodges1,2,31MRC Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, UK2Centre for Clinical Neuroscience and MRC Clinical Sciences Centre, Cardiff University, Cardiff, UK3Prince of Wales Medical Research Institute, Sydney, New South Wales, AustraliaCorrespondence to bcpg1{at

POS07 Reduced ADAMTS-13 activity levels in partial anterior circulation transient ischaemic attack patients compared to nonstroke controls G A Frentzou, C Kamara, K A Harkness, G Haddock, C Doyle, M Taylor, G S Venables, M N Woodroofe, A K Cross, M RandallSheffield Hallam University, Sheffield, UKCorrespondence to G.Frentzou{at}shu.ac.uk AbstractClarification of the pathophysiological mechanisms o

Aims Cognitive impairment in Parkinson's disease (PD) has been associated with both pathological gambling and apathy. The aim of this study is to investigate, by means of a direct comparison, the neuropsychological associations of three behavioural groups of PD sufferers: impulse control disorder (ICD), apathy and controls. Methods Non-demented (n=96) PD sufferers were compared on clinical (motor

Cognitive decline precedes late-life longitudinal changes in vascular risk factors Peter van Vliet, Rudi G J Westendorp, Diana van Heemst, Anton J M de Craen, Anna M OleksikDepartment of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The NetherlandsCorrespondence to Dr P van Vliet, Leiden University Medical Center, Department of Gerontology and Geriatrics (C2-R), PO Box 9600

A diffusion tensor MRI study of patients with MCI and AD with a 2-year clinical follow-up Elisa Scola1, Marco Bozzali2, Federica Agosta3, Giuseppe Magnani4, Massimo Franceschi5, Maria Pia Sormani3,6, Mara Cercignani7, Elisabetta Pagani3, Monica Falautano4, Massimo Filippi3, Andrea Falini11Neuroradiology Unit and CERMAC, Scientific Institute and University Ospedale San Raffaele, Milan, Italy2Neuroi

Differential levels of α-synuclein, β-amyloid42 and tau in CSF between patients with dementia with Lewy bodies and Alzheimer's disease Kensaku Kasuga1,2, Takayoshi Tokutake1,2, Atsushi Ishikawa3, Tsuyoshi Uchiyama4, Takahiko Tokuda5, Osamu Onodera1, Masatoyo Nishizawa2, Takeshi Ikeuchi11Department of Molecular Neuroscience, Brain Research Institute, Niigata University, Niigata, Japan2Department of

Behavioural and psychological symptoms in vascular dementia; differences between small- and large-vessel disease Salka S Staekenborg1, Tanja Su1, Elisabeth C W van Straaten1, Roger Lane2, Philip Scheltens1, Frederik Barkhof3, Wiesje M van der Flier1,41Department of Neurology, Alzheimer Center, Vrije Universiteit Medical Center, Amsterdam, The Netherlands2Novartis Neuroscience, Novartis Pharmaceuti

Bernadette McGuinness1, Suzanne L Barrett2, David Craig1, John Lawson3, A Peter Passmore11Department of Geriatric Medicine Queen's University Belfast, Belfast, UK2Department of Mental Health, Queen's University Belfast, Belfast, UK3Radiology Department, Belfast City Hospital, Belfast, UKCorrespondence to Dr Bernadette McGuinness, Department of Geriatric Medicine, Whitla Medical Building, 97 Lisbur

Blood–brain barrier permeability is increased in normal-appearing white matter in patients with lacunar stroke and leucoaraiosis R Topakian, T R Barrick, F A Howe, H S MarkusClinical Neuroscience, St George's University of London, London, UKCorrespondence to Professor Hugh S Markus, Centre for Clinical Neuroscience, St George's University of London, Cranmer Terrace, London SW17 0RE, UK; hmarkus{at

G Kägi1, K P Bhatia1, E Tolosa21Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London, National Hospital for Neurology and Neurosurgery, London, UK2Parkinson’s Disease and Movement Disorders Unit, Department of Neurology, Hospital Clínic, Institut d’Investigacions Biomèdiques August Pi i Suñer, Universitat de Barcelona, Centro de Investig

Risk of dementia hospitalisation associated with cardiovascular risk factors in midlife and older age: the Atherosclerosis Risk in Communities (ARIC) study A Alonso1, T H Mosley, Jr2, R F Gottesman3, D Catellier4, A R Sharrett5, J Coresh51Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA2Department of Medicine, University o

White matter hyperintensities and medial temporal lobe atrophy in clinical subtypes of mild cognitive impairment: the DESCRIPA study L A van de Pol1, F Verhey2, G B Frisoni3, M Tsolaki4, P Papapostolou5, F Nobili6, L-O Wahlund7, L Minthon8, L Frölich9, H Hampel10, H Soininen11, D L Knol12, F Barkhof13, P Scheltens1, P J Visser21Department of Neurology, Alzheimer Centre, VU Medical Centre, Amsterda