Systemic Inflammation Is Associated with MCI and Its Subtypes: The Sydney Memory and Aging Study
Abstract Background/Aims: Raised low-grade systemic inflammation has been associated with dementia, and preliminary studies suggest an association with mild cognitive impairment (MCI). This study examines the relationship between systemic inflammation and MCI subtypes. Methods: We measured the inflammatory markers C-reactive protein, interleukins (IL)-1β, -6, -8, -10 and -12, plasminogen activator
Association between Body Mass Index and Cognitive Function among Chinese Nonagenarians/Centenarians
Abstract Aims: We examined the individual association between body mass index (BMI) and cognitive function among the very elderly. Methods: The present study analyzed data from a survey that was conducted on all residents aged 90 years or more from a district which had 2,311,709 inhabitants in 2005. The subjects were divided into 4 groups according to quartiles of BMI (<16.6, 16.6–18.9, 18.9–21.1
Epidemiology of Vascular Ageing-MRI研究：片頭痛と脳病変 | 内科開業医のお勉強日記
横断住民ベースの、 Epidemiology of Vascular Ageing-MRI 研究で、重症頭痛既往ある人は、白質hyperintensity増加容積の増加と関連する。前兆を伴う片頭痛は脳梗塞と関連する唯一の頭痛であった。 頭痛はどのタイプであるか、また、脳の病変の組み合わせのどれが認知機能障害と関連するかのエビデンスは不足。 前兆ありの片頭痛と脳の構造との関連は今後の課題であり、特異的サブグループに限定した話か、また予防的戦略はどうかというのが今後研究されるべき。 Headache, migraine, and structural brain lesions and function: population based Epidemiology of Vascular Ageing-MRI study BMJ 2011; 342:c7357 doi: 10.1136/bmj
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Age and coumarin-type anticoagulation are associated with the occurrence of intraplaque hemorrhage, while statins are associated less with intraplaque hemorrhage: A large histopathological study in carotid and femoral plaques
Coated-platelet levels and progression from mild cognitive impairment to Alzheimer disease