Changes in Vascular Risk Factors from Midlife to Late Life and White Matter Lesions: A 20-Year Follow-Up Study Vuorinen M.e · Solomon A.a, e · Rovio S.a · Nieminen L.e · Kåreholt I.a · Tuomilehto J.b–d · Soininen H.e–g · Kivipelto M.a, e Author affiliations aAging Research Center, NVS, Karolinska Institute, Stockholm, Sweden; bDepartment of Epidemiology and Health Promotion, National Public Health

Abstract Background: The Ε4 allele of apolipoprotein E (APOE) is associated with Alzheimer’s disease (AD). However, attributable risk due to APOE4 varies by region and by race/ethnicity. Methods: A literature review and meta-analysis were conducted to estimate the prevalence of APOE4 by geographic area among AD patients. Results: Although estimates varied significantly by study design and case def

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Prevalence of Mild Cognitive Impairment and Its Subtypes in the Heinz Nixdorf Recall Study Cohort Dlugaj M.a · Weimar C.a · Wege N.b · Verde P.E.c · Gerwig M.a · Dragano N.b · Moebus S.d · Jöckel K.-H.d · Erbel R.e · Siegrist J.b Author affiliations aDepartment of Neurology, University Hospital Essen, Essen, bDepartment of Medical Sociology and cCoordination Center for Clinical Trials, University

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日経メディカル運営の「日本最大級」医師求人メディア。転職支援会社が扱う求人情報のほか、医療機関からの直接求人情報も掲載！

Choices, Attitudes, and Strategies for Care of Advanced Dementia at the End-of-Life (CASCADE) 研究からの認知症進行期の臨床経過を前向きにみたもの 結論は、”米国ナーシングホームでの進行期認知症への、緩和的ケアへの対応は不十分で、死因は感染症と嚥下問題が主”、”ナーシングホーム在居認知症進行期の死亡率検討し、6ヶ月で半数以上が死亡し、肺炎、熱性エピソード、食事の問題が死因として多い”という報告 どこの先進国でも、認知症を貴院とする死亡数が増加しているが、どこの国でも死亡・最適な緩和ケアに関する認識が低い。認知症は、癌や動脈硬化性疾患と同じく、誰もが罹患する疾患であり、自分もしくは親戚、知人だれかが罹患する可能性がある。そのリスクに関する認識を持つ必要がある。 また、膨大な社会保障費が費やされており、

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喫煙者、高血圧、糖尿病いづれかを有する中年は認知症発症後年生じやすい Alonso A, Mosley T, Gottesman T, et al. Risk of dementia hospitalization associated with cardiovascular risk factors in midlife and older age: the Atherosclerosis Risk in Communities (ARIC) study. J Neurol Neurosurg Psychiatry 2009; DOI:10.1136/jnnp.2009.176818. 2009年8月19日オンライン出版の文献、 Journal of Neurology, Neurosurgery and Psychiatryで、認知症発症のリスク報告 中年での心血管リスク要因が後年の認

Framingham based primary cardiovascular risk calculator:http://www.patient.co.uk/showdoc/40000133/ QRISK®2 cardiovascular disease risk calculator:http://www.qrisk.org/ 以下の論文の結論は、QRISK cardiovascular disease risk equationは、 Anderson Framingham equationより、UKでの心血管疾患・高リスク・ポピュレーションを同定に改善をもたらす。QRISKは10年の心血管疾患リスクを過小評価するが、過小予測に関してはAnderson Framinghamより少ない。 An independent external validation and evaluation

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The .gov means it’s official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site. The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.