[Edit] By popular demand, I've added a section on PyGTK. See bottom of post. There are several platforms for programming Windows GUI applications in Python. Below I outline a few of them, with a simple "hello world" example for each. Where I've lifted the example from another site, there's a link to the source. Contents Tkinter wxPython IronPython PyQT Pyglet Win32 with ctypes (warning: long!) Ven