非定型的パーキンソニズムにおけるBicycle sign - Neurology 興味を持った「脳神経内科」論文
Lancet誌に非定型的パーキンソニズムとパーキンソン病の鑑別に有用な方法が報告されている．ただ「自転車に乗れますか？」と質問するのである． 診断が確定していない156名のパーキンソニズムを呈する患者に対し，前向き観察研究が行われた．最初の段階で111名が自転車に乗れた．罹病期間が30ヶ月経過した後，臨床的にパーキンソン病45名，非定型的パーキンソニズム66名（MSA 35名，PSP 9名，LBD 3名，CBS 2名，血管性パーキンソニズム 17名）と診断された．パーキンソン病では2名（2/45；4.4%）が自転車に乗れなくなっていたが，非定型的パーキンソニズムでは34名（66；51.5%）が自転車に乗れなくなっていた． これをBicycle signとして，診断への有用性を評価すると，感度52%，特異度96%，AUC（area under curve）0.74と良好な結果であった．回帰分
Dysexecutive versus amnesic phenotypes of very mild Alzheimer's disease are associated with distinct clinical, genetic and cortical thinning characteristics
Dysexecutive versus amnesic phenotypes of very mild Alzheimer's disease are associated with distinct clinical, genetic and cortical thinning characteristics Bradford C Dickerson1,2,3,4, David A Wolk5,6,7, the Alzheimer's Disease Neuroimaging Initiative1Frontotemporal Dementia Unit, Boston, Massachusetts, USA2Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston
Tongue Fasciculations
Fasciculations are visible, irregular, and involuntary contractions of individual muscle fibers caused by lower motor neurons damage to hypoglossal nerve. This video shows fasciculations of intrinsic tongue muscles secondary to left lingual nerve involvement in metastatic cervical lymph nodes. The tongue deviated to the left on protrusion.
Apathy and the Functional Anatomy of the Prefrontal Cortex–Basal Ganglia Circuits
Abstract The clinical signs grouped under the concept of apathy are a common feature of prefrontal and basal ganglia lesions or dysfunctions and can therefore help to improve our understanding of the functional anatomy of the prefrontal–basal ganglia system. Apathy is here defined as a quantitative reduction of voluntary, goal-directed behaviors. The underlying mechanisms responsible for apathy ca
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Pattern of language impairment is different in Alzheimer's disease and multi-infarct dementia - PubMed
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Prophylaxis of migraine with melatonin: A randomized controlled trial -- Alstadhaug et al. 75 (17): 1527 -- Neurology
A randomized controlled trial Karl B. Alstadhaug, MD, PhD, Francis Odeh, MD, PhD, Rolf Salvesen, MD, PhD and Svein I. Bekkelund, MD, PhD From the Department of Neurology (K.B.A., F.O., R.S.), Nordlandssykehuset Bodø, Bodø; Department of Neurology (S.I.B.), University Hospital of North Norway, Tromsø; and Institute of Clinical Medicine (K.B.A., R.S., S.I.B.), University of Tromsø, Tromsø, Norway. A
PAW20 Saccadic correlates of cognition in progressive supranuclear palsy
B Ghosh1,2,3, J B Rowe1,2,3, R H S Carpenter1,2,3, A J Calder1,2,3, P V Peers1,2,3, A D Lawrence1,2,3, J R Hodges1,2,31MRC Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, UK2Centre for Clinical Neuroscience and MRC Clinical Sciences Centre, Cardiff University, Cardiff, UK3Prince of Wales Medical Research Institute, Sydney, New South Wales, AustraliaCorrespondence to bcpg1{at
[A case with trigeminal herpes zoster manifesting a long lesion of the spinal trigeminal nucleus and tract on MR T2-weighted image] - PubMed
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Radiofrequency trigeminal rhizolysis for the treatment of trigeminal neuralgia secondary to brainstem infarction. Report of two cases - PubMed
The .gov means it’s official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site. The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Topographical disorientation: a synthesis and taxonomy
Abstract Over the last century, several dozen case reports have presented `topographically disoriented' patients who, in some cases, appear to have selectively lost their ability to find their way within large-scale, locomotor environments. A review is offered here that has as its aim the creation of a taxonomy that accurately reflects the behavioural impairments and neuroanatomical findings of th
Psychiatry Research: Neuroimaging | Journal | ScienceDirect.com by Elsevier
Psychiatry Research: Neuroimaging, a companion title to Psychiatry Research, focuses on publications relating to imaging techniques. We publish manuscripts on magnetic resonance imaging, positron emission tomography, multichannel electrophysiology, near-infrared spectroscopy, computed tomography, magnetoencephalography, non-invasive brain stimulation, autoradiography, post-mortem regional analyses
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Elevated Intracranial Pressures in Spontaneous Cerebrospinal Flui...: Ingenta Connect
Elevated Intracranial Pressures in Spontaneous Cerebrospinal Fluid Leaks The full text article is temporarily unavailable. We apologise for the inconvenience. Please try again later. Background: Spontaneous cerebrospinal fluid (CSF) leak is a condition that previously has been considered idiopathic and classified as having "normal" intracranial pressure (ICP). We present clinical and radiographic
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救急部門でくも膜下出血リスクの高い頭痛患者を見分けるルール
https://www.ahajournals.org/doi/full/10.1161/strokeaha.107.493353
Psychiatry Online
Small medullary infarction presenting as painful trigeminal sensory neuropathy.
Karger Publishers
Meningitis
