Cell type-specific and time-dependent light exposure contribute to silencing in neurons expressing Channelrhodopsin-2
Channelrhodopsin-2 (ChR2) has quickly gained popularity as a powerful tool for eliciting genetically targeted neuronal activation. However, little has been reported on the response kinetics of optogenetic stimulation across different neuronal subtypes. With excess stimulation, neurons can be driven into depolarization block, a state where they cease to fire action potentials. Herein, we demonstrat
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Brain-wide mapping of neural activity controlling zebrafish exploratory locomotion
Contrasting roles for parvalbumin-expressing inhibitory neurons in two forms of adult visual cortical plasticity
Optogenetic feedback control of neural activity
CaRuby-Nano: a novel high affinity calcium probe for dual color imaging
Low cost, high performance processing of single particle cryo-electron microscopy data in the cloud
A cortical disinhibitory circuit for enhancing adult plasticity
Synaptotagmin 7 functions as a Ca2+-sensor for synaptic vesicle replenishment
Dynamin phosphorylation controls optimization of endocytosis for brief action potential bursts
Changing the responses of cortical neurons from sub- to suprathreshold using single spikes in vivo