NIH to evaluate effectiveness of male contraceptive skin gel
Researchers plan to enroll approximately 420 couples in clinical trial. A clinical trial funded by the National Institutes of Health will evaluate a male contraceptive gel for its ability to prevent pregnancy. The gel formulation was developed by the Population Council and NIH’s Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). The Population Council will col
Study finds mindfulness meditation offers relief for low-back pain
Study finds mindfulness meditation offers relief for low-back pain Mindfulness based stress reduction (MBSR) and cognitive-behavioral therapy (CBT) may prove more effective than usual treatment in alleviating chronic low-back pain, according to a new study funded by the National Center for Complementary and Integrative Health (NCCIH), part of the National Institutes of Health. “It is vital that we
NIH Clinical Center releases dataset of 32,000 CT images
The National Institutes of Health’s Clinical Center has made a large-scale dataset of CT images publicly available to help the scientific community improve detection accuracy of lesions. While most publicly available medical image datasets have less than a thousand lesions, this dataset, named DeepLesion, has over 32,000 annotated lesions identified on CT images. The images, which have been thorou
Essential malaria parasite genes revealed
NIAID-funded research could aid antimalarial drug development Electron micrograph of red blood cells infected with Plasmodium falciparum, the parasite that causes malaria in humans. During its development, the parasite forms protrusions called 'knobs' on the surface of its host red blood cell which enable it to avoid destruction and cause inflammation. Using scanning electron microscopy, this imag
Mental disorders may share molecular origins
At a Glance Patterns of gene expression in the brains of people with five major mental disorders suggest some overlapping mechanisms. The findings help provide a framework for understanding the processes that affect the risk for developing mental disorders. Scientists have been exploring patterns of gene activity in the brains of people with mental disorders.kirstypargeter/iStock/ThinkstockI About
Omalizumab improves efficacy of oral immunotherapy for multiple food allergies
Omalizumab improves efficacy of oral immunotherapy for multiple food allergies What Combining a 16-week initial course of the medication omalizumab with oral immunotherapy (OIT) greatly improves the efficacy of OIT for children with allergies to multiple foods, new clinical trial findings show. After 36 weeks, more than 80 percent of children who received omalizumab and OIT could safely consume tw
NIH study identifies brain patterns underlying mothers’ responses to infant cries
NIH study identifies brain patterns underlying mothers’ responses to infant cries Behaviors and brain activity consistent between mothers from different countries. What Infant cries activate specific brain regions related to movement and speech, according to a National Institutes of Health study of mothers in 11 countries. The findings, led by researchers at NIH’s Eunice Kennedy Shriver National I
Ovarian reserve tests fail to predict fertility, NIH-funded study suggests
Ovarian reserve tests fail to predict fertility, NIH-funded study suggests Hormones linked to onset of menopause not associated with chances of conception. Tests that estimate ovarian reserve, or the number of a woman’s remaining eggs, before menopause, do not appear to predict short-term chances of conception, according to a National Institutes of Health-funded study of women with no history of i
NIH researchers uncover drain pipes in our brains
Results provide first evidence of the body’s waste system in the human brain. A brain drainage system - Brain scans of healthy volunteers showed that our brains may drain waste through lymphatic vessels, the body’s sewer system. Reich Lab, NIH/NINDS. By scanning the brains of healthy volunteers, researchers at the National Institutes of Health saw the first, long-sought evidence that our brains ma
NIH Clinical Center provides one of the largest publicly available chest x-ray datasets to scientific community
NIH Clinical Center provides one of the largest publicly available chest x-ray datasets to scientific community The dataset of scans is from more than 30,000 patients, including many with advanced lung disease. What The NIH Clinical Center recently released over 100,000 anonymized chest x-ray images and their corresponding data to the scientific community. The release will allow researchers across
Three-in-one antibody protects monkeys from HIV-like virus
NIH and Sanofi scientists prepare to test antibody in people. Diagram of the “three-in-one” HIV antibody. The blue, purple and green segments each bind to a different critical site on the virus. Sanofi A three-pronged antibody made in the laboratory protected monkeys from infection with two strains of SHIV, a monkey form of HIV, better than individual natural antibodies from which the engineered a
Dr. James Ostell named Director of the National Center for Biotechnology Information
Dr. James Ostell named Director of the National Center for Biotechnology Information National Library of Medicine (NLM) Director Patricia Flatley Brennan, R.N., Ph.D., has appointed James M. Ostell, Ph.D., as the director of the National Center for Biotechnology Information (NCBI), a division of NLM at the National Institutes of Health. Dr. Ostell has been with NCBI since it was established by Co
Zika virus selectively infects and kills glioblastoma cells in mice
Zika virus selectively infects and kills glioblastoma cells in mice Transmission electron microscope image of negative-stained, Fortaleza-strain Zika virus (red), isolated from a microcephaly case in Brazil.National Institute of Allergy and Infectious Diseases (NIAID) WHAT: The Zika virus (ZIKV) may infect and kill a specific type of brain cancer cells while leaving normal adult brain tissue minim
In adolescents, oral Truvada and vaginal ring for HIV prevention are safe, acceptable
In adolescents, oral Truvada and vaginal ring for HIV prevention are safe, acceptable NIH-funded clinical trials are first of their kind to include younger adolescent girls. A monthly vaginal ring and a daily oral tablet, both containing anti-HIV drugs, were safe and acceptable in studies of adolescents, two teams of investigators reported today at the 9th IAS Conference on HIV Science in Paris. T
New NIH Approach to Grant Funding Aimed at Optimizing Stewardship of Taxpayer Dollars
New NIH Approach to Grant Funding Aimed at Optimizing Stewardship of Taxpayer Dollars Today we want to put forward a new approach to making sure that we are exercising optimum stewardship of the funds that we receive from taxpayers. We will be discussing this approach with our Advisory Councils over the next few weeks, and so we wanted to provide this broad public description. This initiative aim
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NIH releases first dataset from unprecedented study of adolescent brain development
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