Direct-to-consumer microbiome tests often go beyond what the research can support, but the large databases being generated by some companies are supporting diagnostic development. The researchers developed a catalog of variants found within breed dogs, mixed dogs, village dogs, wolves, and coyotes that will aid future studies.
Sanger Team Analyses Suggest Synthetic Associations Not Behind Most Common Disease GWAS Signals By Andrea Anderson COLD SPRING HARBOR, NY (GenomeWeb News) – Synthetic associations between rare, disease-causing variants and common variants probably explain relatively few of the signals detected in genome-wide association studies of common disease, according to Wellcome Trust Sanger Institute human
PacBio Shows Proof of Principle for Methylation Sequencing, Direct RNA Sequencing By Julia Karow This article was originally published Sept. 17. COLD SPRING HARBOR, NY – Pacific Biosciences has demonstrated that it can use its single-molecule real-time sequencing technology to identify methylated DNA bases, and to directly sequence RNA molecules. It has also applied strobe sequencing, a sequencing
ABI Says SOLiD Found More Forms of Variation in HapMap than Illumina; No Formal Comparison Yet By Julia Karow Applied Biosystems' SOLiD platform discovered more forms of genome variation in a HapMap sample with less coverage than Illumina's Genome Analyzer did in a previous analysis of the same sample, although the overall number of variations discovered was smaller, according to an ABI researcher
Researchers Sequence Korean Genome; Find Many Differences with Other Sequenced Human Genomes This article has been corrected to note that the genome sequenced is that of Seong-Jin Kim, the project leader, not that of an unidentified donor. Researchers at Gachon University of Medicine and Science in Korea and at the Korean BioInformation Center have sequenced the genome of a Korean individual and h
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