Arch Neurol -- Abstract: Longitudinal Changes in White Matter Disease and Cognition in the First Year of the Alzheimer Disease Neuroimaging Initiative, November 2010, Carmichael et al. 67 (11): 1370

Example white matter hyperintensity (WMH) detection results for 3 individuals whose WMH distributions are representative of the broader sample. Detected WMHs are overlaid in white on slices of T1-weighted images. Each row shows a set of 3 slices for a given individual. Each column shows detection at an analogous slice across all 3 individuals. The 3 individuals differ in their WMH distribution: th

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白質病変の容積が1年後のAD患者のADAS-cogの上昇、MMSEの低下に相関した。

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白質病変の容積が1年後のAD患者のADAS-cogの上昇、MMSEの低下に相関した。