This page last changed on January 28, 2016 by peterk. The page provides download links to an R package for processing ChIP-seq data. The rational behind most of the methods is described in the following paper: Kharchenko PK, Tolstorukov MY, Park PJ "Design and analysis of ChIP-seq experiments for DNA-binding proteins" Nat. Biotech. doi:10.1038/nbt.1508 version 1.13Download. SPP is now on Github! v