β-Amyloid accumulation in the human brain after one night of sleep deprivation
β-Amyloid accumulation in the human brain after one night of sleep deprivation View ORCID ProfileEhsan Shokri-Kojori, Gene-Jack Wang, Corinde E. Wiers, Sukru B. Demiral, Min Guo, Sung Won Kim, Elsa Lindgren, Veronica Ramirez, Amna Zehra, Clara Freeman, Gregg Miller, Peter Manza, Tansha Srivastava, Susan De Santi, Dardo Tomasi, Helene Benveniste, and Nora D. Volkow aLaboratory of Neuroimaging, Nati
Coupling mutagenesis and parallel deep sequencing to probe essential residues in a genome or gene
Coupling mutagenesis and parallel deep sequencing to probe essential residues in a genome or gene aDepartment of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115; andbMolecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Mohakhali, Dhaka 1212, Bangladesh
Tunable synthetic phenotypic diversification on Waddington’s landscape through autonomous signaling
Tunable synthetic phenotypic diversification on Waddington’s landscape through autonomous signaling Ryoji Sekine, Masayuki Yamamura, Shotaro Ayukawa, Kana Ishimatsu, Satoru Akama, Masahiro Takinoue, Masami Hagiya, and Daisuke Kiga aDepartment of Computational Intelligence and Systems Science, Tokyo Institute of Technology, Kanagawa 226-8503, Japan; bDepartment of Computer Science, University of To
How social influence can undermine the wisdom of crowd effect
AbstractSocial groups can be remarkably smart and knowledgeable when their averaged judgements are compared with the judgements of individuals. Already Galton [Galton F (1907) Nature 75:7] found evidence that the median estimate of a group can be more accurate than estimates of experts. This wisdom of crowd effect was recently supported by examples from stock markets, political elections, and quiz
Exercise training increases size of hippocampus and improves memory
Exercise training increases size of hippocampus and improves memory Kirk I. Erickson, Michelle W. Voss, Ruchika Shaurya Prakash, Chandramallika Basak, Amanda Szabo, Laura Chaddock, Jennifer S. Kim, Susie Heo, Heloisa Alves, Siobhan M. White, Thomas R. Wojcicki, Emily Mailey, Victoria J. Vieira, Stephen A. Martin, Brandt D. Pence, Jeffrey A. Woods, Edward McAuley, and Arthur F. Kramer aDepartment o
The human disease network
Abstract A network of disorders and disease genes linked by known disorder–gene associations offers a platform to explore in a single graph-theoretic framework all known phenotype and disease gene associations, indicating the common genetic origin of many diseases. Genes associated with similar disorders show both higher likelihood of physical interactions between their products and higher express
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Intergenerational transmission of emotional trauma through amygdala-dependent mother-to-infant transfer of specific fear
Acetylated histone H3K56 interacts with Oct4 to promote mouse embryonic stem cell pluripotency
Predictive microfluidic control of regulatory ligand trajectories in individual pluripotent cells
Digital RNA sequencing minimizes sequence-dependent bias and amplification noise with optimized single-molecule barcodes | PNAS
Spatio-temporal correlations can drastically change the response of a MAPK pathway | PNAS
Single-cell proteomic chip for profiling intracellular signaling pathways in single tumor cells | PNAS
Regulatory elements required for the activation and repression of the protocadherin-α gene cluster
Distinct histone modifications in stem cell lines and tissue lineages from the early mouse embryo | PNAS
Model-based method for transcription factor target identification with limited data
A Bayesian model predicts the response of axons to molecular gradients
Sequence information can be obtained from single DNA molecules
Human embryonic stem cell phosphoproteome revealed by electron transfer dissociation tandem mass spectrometry
Noisy information processing through transcriptional regulation
http://www.pnas.org/cgi/content/abstract/0606169104v1