「ＳＴＡＰ細胞オールジャパンで」…山中教授 : ニュース : 関西発 : YOMIURI ONLINE（読売新聞）
様々な細胞に変化できるｉＰＳ細胞（人工多能性幹細胞）を開発し、２０１２年にノーベル生理学・医学賞を受賞した山中伸弥・京都大教授（５１）＝写真＝が５日、読売新聞の単独インタビューに応じた。強い刺激によってｉＰＳ細胞と同様の能力を持つように変化するＳＴＡＰ（スタップ）細胞の作製について、「画期的な成果。オールジャパンで研究を進めるべきで、いくらでも協力する」と話し、ＳＴＡＰ細胞の研究を進める理化学研究所発生・再生科学総合研究センター（神戸市）に共同研究を呼びかける意向を示した。 研究の中心となった同センターの小保方(おぼかた)晴子・研究ユニットリーダー（３０）を「素晴らしい発想の持ち主」とたたえ、「（山中教授が所長を務める）京大ｉＰＳ細胞研究所の若い研究者と小保方さんが協力すれば、細胞が受精卵のような状態に戻る『初期化』の謎について、大発見ができるかもしれない」と期待を寄せた。 今夏にも目の難
A Guide to the Go Garbage Collector - The Go Programming Language
Introduction This guide is intended to aid advanced Go users in better understanding their application costs by providing insights into the Go garbage collector. It also provides guidance on how Go users may use these insights to improve their applications' resource utilization. It does not assume any knowledge of garbage collection, but does assume familiarity with the Go programming language. Th
Robust Git Support. Powerful Workspace Improvements. Professional Font Feature Support. See the full release notes!! A powerful editor. Flexible workflows. Helpful debugging. Useful tools. Robust extensions. And lots of settings. The Editor. It all starts with our first-class text-editor. It's new, hyper-fast, and flexible, with all the features you want: smart autocomplete, multiple cursors, a Mi
How We Saved 70K Cores Across 30 Mission-Critical Services (Large-Scale, Semi-Automated Go GC Tuning @Uber)
How We Saved 70K Cores Across 30 Mission-Critical Services (Large-Scale, Semi-Automated Go GC Tuning @Uber) Introduction As part of Uber engineering’s wide efforts to reach profitability, recently our team was focused on reducing cost of compute capacity by improving efficiency. Some of the most impactful work was around GOGC optimization. In this blog we want to share our experience with a highly
40 Useful jQuery Techniques and Plugins — Smashing Magazine
Over the last year, Smashing Magazine has evolved. We’ve been publishing fewer lists and more in-depth articles about design and Web development. We have invited professionals and high-profile developers to write for us. We’ve been investing more resources in the quality and relevance of our articles. We’ve also explored new formats; and on weekends we’ve been publishing more inspirational pieces,
perldelta - perl v5.8.9 の新機能
perldelta - perl v5.8.9 の新機能 perldelta - what is new for perl v5.8.9 名前 NAME perldelta - perl v5.8.9 の新機能 perldelta - what is new for perl v5.8.9 説明 DESCRIPTION このドキュメントでは 5.8.8 リリースと 5.8.9 リリースとでの相異点を 説明します. This document describes differences between the 5.8.8 release and the 5.8.9 release. Notice 5.8.9 リリースは 5.8.x シリーズにおける最後の大きなリリースと なるでしょう. 5.8.x の今後のリリースは恐らくセキュリティに関する物か プラットフォームにおけるビルド不具合のみの
We are pleased to announce version 5.0.0 of Angular, pentagonal-donut. This is a major release containing new features and bugfixes. This release continues our focus on making Angular smaller, faster, and easier to use. Here’s a breakdown of some of the biggest changes in v5. For the full list, please see the changelog. Build OptimizerAs of 5.0.0, production builds created with the CLI will now ap
Quintus is an easy-to-learn, fun-to-use JavaScript HTML5 game engine for mobile, desktop and beyond!Demo Game a platfomer in ~80 lines of code, you can edit the code on the left. Click to focus, arrow keys to move. more var Q = Quintus() .include("Sprites, Scenes, Input, 2D, Touch, UI") .setup({ maximize: true }) .controls().touch() Q.Sprite.extend("Player",{ init: function(p) { this._super(p, { s
Puppeteer, Selenium, Playwright, Cypress - how to choose? - AI-driven E2E automation with code-like flexibility for your most resilient tests
Puppeteer, Selenium, Playwright, Cypress – how to choose? At Testim, a lot of what we do is build AI-based features on top of automation frameworks to add stability,… At Testim, a lot of what we do is build AI-based features on top of automation frameworks to add stability, accelerate test creation, and improve root-cause analysis. We evaluate a number of test automation frameworks to understand
Tablet
This is a concept UI under development. Designs are subject to change. This page contains visual explorations of how a Chrome OS tablet UI might look in hardware. Some possibilites they explore include: Keyboard interaction with the screen: anchored, split, attached to focus. Launchers as an overlay, providing touch or search as means to access web sites. Contextual actions triggered via dwell. Zo
Rails is great for making traditional server-rendered web applications. It has support for cookies, sessions, and other browser-specific functionality right out of the box. It's also great for building JSON APIs, but why include a whole bunch of functionality that we aren't going to use if what we want is to simply build a JSON API? That's where using Rails in --api mode comes in handy. It gives u
`undefined` vs. `null` revisited
Many programming languages have one “non-value” called null. It indicates that a variable does not currently point to an object – for example, when it hasn’t been initialized yet. In contrast, JavaScript has two such non-values: undefined and null. In this blog post, we examine how they differ and how to best use or avoid them. undefined vs. null # Both values are very similar and often used inte
1. Document Object Model Events Editors Tom Pixley, Netscape Communications Corp. 1.1. Overview of the DOM Level 2 Event Model The DOM Level 2 Event Model is designed with two main goals. The first goal is the design of a generic event system which allows registration of event handlers, describes event flow through a tree structure, and provides basic contextual information for each event. Additio
Browser-level image lazy loading for the web Stay organized with collections Save and categorize content based on your preferences. You can use the loading attribute to lazy-load images without the need to write custom lazy-loading code or use a separate JavaScript library. Here's a demo of the feature: Lazy-loaded images load as the user scrolls through the page. This page walks through the detai
皆様うるう秒対応お疲れ様でした。こんにちはこんにちは！！インフラ基盤サービスグループという名前のアレに所属させてもらって、画像配信基盤とかネイティブアプリ基盤などのインフラの面倒を見させてもらってる、@kakerukaeruと申します。 副業でジャック・ニコル◯ンの偽物をしたり社内chatにAAや画像を貼って場を荒らす和ませる仕事をしております。 はいというわけで、 ここ最近うるう秒対策チームを私と@nekoruriさんの二人でやっていたのですが、 せっかくだからウチはこういう対策やったよ、ってのを 「you エンジニアブログに書いちゃいなよ」って雑談から始まり、 「me エンジニアブログに書いちゃいなよ(?)」となり、 公式エンジニアブログに初参戦させていただく運びと相成りました。 もううるう秒終わってんじゃねーか、うるう秒の前に公開しろや。とは僕も思いますが、突っ込まないで下さい うる
Practical Web Cache Poisoning | PortSwigger Web Security Blog
Published: 09 August 2018 at 23:20 UTC Updated: 02 October 2023 at 14:39 UTC AbstractWeb cache poisoning has long been an elusive vulnerability, a 'theoretical' threat used mostly to scare developers into obediently patching issues that nobody could actually exploit. In this paper I'll show you how to compromise websites by using esoteric web features to turn their caches into exploit delivery sys
The Document Object Model (DOM) connects web pages to scripts or programming languages by representing the structure of a document—such as the HTML representing a web page—in memory. Usually, that means JavaScript, although modeling HTML, SVG, or XML documents as objects are not part of the core JavaScript language, as such. The DOM represents a document with a logical tree. Each branch of the tre
Tutorial: OpenCV haartraining (Rapid Object Detection With A Cascade of Boosted Classifiers Based on Haar-like Features) - Naotoshi Seo
Objective The OpenCV library provides us a greatly interesting demonstration for a face detection. Furthermore, it provides us programs (or functions) that they used to train classifiers for their face detection system, called HaarTraining, so that we can create our own object classifiers using these functions. It is interesting. However, I could not follow how OpenCV developers performed the haar
HTTP/2 (and H2O) improves user experience over HTTP/1.1 or SPDY
HTTP/2 (and H2O) improves user experience over HTTP/1.1 or SPDY HTTP/2 is expected to offer better user experience than HTTP/1.1, the unanswered question is how much the benefit is in practice. Tonight I have given a presentation regarding the issue, showing HTTP/2 performance of H2O HTTP server at shibuya.pm, a popular technology meetup at Tokyo. This blog post is a summary of the presentation at
新たな万能細胞とされた「ＳＴＡＰ細胞」論文問題がメディアをにぎわしているが、万能細胞研究者ではない筆者にその科学的真偽は判断できない。しかし、英国で発行されている権威ある科学誌「ネイチャー」に掲載された論文についての議論はあまりにもいい加減で、報道も理化学研究所（理研）や共著者に対する批判や糾弾だけに終始している。「金のなる木」にむらがる 「刺激惹起性多能性獲得」（Ｓｔｉｍｕｌｕｓ Ｔｒｉｇｇｅｒｅｄ Ａｃｑｕｉｓｉｔｉｏｎ ｏｆ Ｐｌｕｒｉｐｏｔｅｎｃｙ）の頭文字から命名されたＳＴＡＰ細胞は、小保方晴子研究ユニットリーダー（３０）を中心とするグループが作製に「成功した」と発表されたもの。２０１２年度のノーベル生理学・医学賞を授与された山中伸弥氏らのグループが開発した人工多能性幹細胞（ｉＰＳ細胞）よりもはるかに簡単な方法で、万能細胞を作製できたとの説明がなされ、世界を驚愕（きょうがく）させ
OpenAI’s CEO Says the Age of Giant AI Models Is Already Over
The stunning capabilities of ChatGPT, the chatbot from startup OpenAI, has triggered a surge of new interest and investment in artificial intelligence. But late last week, OpenAI’s CEO warned that the research strategy that birthed the bot is played out. It's unclear exactly where future advances will come from. OpenAI has delivered a series of impressive advances in AI that works with language in
UPDATE: I now believe the best explanation for Unit 3 is an ex-vessel steam explosion: http://iangoddard.com/fukushima01.html A steam explosion does not exclude a nuclear criticality as considered in this video (in fact the explosion of the Borax test reactor was both a criticality and a steam explosion http://youtu.be/8WfNzJVxVz4?t=13m27s ), but at the same time a steam explosion does not requir
Earthquake in Chile
At 3:34 am local time, today, February 27th, a devastating magnitude 8.8 earthquake struck Chile, one of the strongest earthquakes ever recorded. According to Chilean authorities, over 400 people are now known to have been killed. The earthquake also triggered a Tsunami which is right now propagating across the Pacific Ocean, due to arrive in Hawaii in hours (around 11:00 am local time). The sever
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Sci-Fi Hi-Fi: Cocoalicious
Login Problem Fix This latest update (b45) should finally fix the longstanding login problem with Cocoalicious and the new del.icio.us API URL. Thanks for your patience, and sorry it took so long! What is Cocoalicious? Cocoalicious is a del.icio.us client for Mac OS X. It acts as a desktop interface to your del.icio.us bookmarks Cocoalicious is open source, available under the terms of the BSD Lic
仕込み筋肉３号機 Muscle System | 脳波で膨張 detect brain waves | 森翔太 #ShotaMori 女子高生 #Japanese school girl
強くなりたい、という男の永遠の夢を叶える夢のスーツ「仕込み筋肉 3号機」が完成した。このスーツは、脳波を探知し、集中力が一定値を超える事により空気圧の弁が開き、身体を膨らませなおかつ、二酸化炭素の煙を立ち上がらせる機能をつけることで、強そうな人物に変身できる「脳波探知式二酸化炭素噴出型筋肉膨張スーツ」である。 The Brainwave Controlled Muscle Suit Ver. 3 is here to make dreams come true for any man who ever wished to become stronger. When the suit detects the user concentrating above a certain baseline brainwave reading, a pneumatic valve is triggered
Upgrading GitHub to Ruby 2.7
EngineeringUpgrading GitHub to Ruby 2.7GitHub recently upgraded to Ruby 2.7. Learn how the team approached the deprecation warnings, why upgrading is important, and the notable performance improvements. After many months of work, we deployed GitHub to production using Ruby 2.7 in July. For those who aren’t familiar with GitHub’s stack, we’ve been running on Ruby since the beginning. Many years ago
日本の国際ジャーナリストさんとかがぶちまけるヘタな陰謀論のような図柄でもあるが、「ウォール街占拠」運動にはどうも、うさんくさい影がある。本当に自然着火なのだろうか。 欧米では「これってソロスが後ろで糸を引いているのではないか」という噂があり、しかも、リンボーあたりが気炎を吐いているならば、苦笑して通り過ぎるのが常識人だし、お利口さんならクラウトハマーのように「馬鹿なスケープゴート運動やりやがって」（参照）とかするのが定番だが、どうもそれで納めるにはなんとも、嫌な印象が残る。 と思っていたところに、ロイターが直球に見せかけてクセ玉を投げ込んだ。13日付け「焦点：格差是正求める反ウォール街デモ、背後に富豪ソロス氏の影」（参照）である。長いがジャーナリズム検証の意味もあってあえて引用したい。 ［ニューヨーク １３日 ロイター］ 米国でニューヨークから各地に広がっている「反ウォール街デモ」は、平均
さくら、「レンタルサーバ」サービスに国外IPフィルタ設定を適用へ：OpenFlowを活用したDDoS対策機能も提供予定 さくらインターネットは不正アクセス対策を目的に、「さくらのレンタルサーバ」サービスにおいて、国外IPアドレスからのアクセスを制限する「国外IPフィルタ設定」機能を提供する。 さくらインターネットは2014年3月10日、不正アクセス対策を目的に、「さくらのレンタルサーバ」サービスにおいて、国外IPアドレスからのアクセスを制限する「国外IPフィルタ設定」機能を提供することを明らかにした。2014年3月13日より順次、設定作業を開始する。 国外IPフィルタ機能の対象となるのは、「さくらのマネージドサーバ」「さくらのメールボックス」も含む「さくらのレンタルサーバ」サービスだ。FTP、SSH、SMTP（SMTP認証、POP before SMTP時を含む）、WebDAVの各プロトコ
Bash Pitfalls This page is a compilation of common mistakes made by bash users. Each example is flawed in some way. 1. for f in $(ls *.mp3) One of the most common mistakes BASH programmers make is to write a loop like this: for f in $(ls *.mp3); do # Wrong! some command $f # Wrong! done for f in $(ls) # Wrong! for f in `ls` # Wrong! for f in $(find . -type f) # Wrong! for f in `find . -type f` # W
How is it possible that JavaScript-based animation has secretly always been as fast — or faster — than CSS transitions? And, how is it possible that Adobe and Google consistently release media-rich mobile sites that rival the performance of native apps? This article serves as a point-by-point walkthrough of how JavaScript-based DOM animation libraries, such as Velocity.js and GSAP, are more perfor
On 11 March 2011, at 14:46 JST (05:46 UTC), a Mw 9.0–9.1 undersea megathrust earthquake occurred in the Pacific Ocean, 72 km (45 mi) east of the Oshika Peninsula of the Tōhoku region. It lasted approximately six minutes and caused a tsunami. It is sometimes known in Japan as the "Great East Japan Earthquake" (東日本大震災, Higashi nihon daishinsai), among other names.[en 1] The disaster is often referre
With rajaplay alternatif may be added towards racing approach. You can race more than one car per slot and change lanes, make passing moves or blocking moves, program in pits tops, ghost cars, yellow flags etc. The reason much much more the real motor training. There are sets where perform race 8 cars meanwhile on a two lane slot car made. They are more expensive n comparison to the analog batches
Double Da Vinci Diamonds is the sequel to the hugely popular Da Vinci Diamonds game. It is a slot machine developed by IGT which has 5 reels and 40 paylines. The graphics are fantastic with several works of art by Leonardo da Vinci and the game does not require any download in addition to being available for American players. Apart from being available for real money, there is also a free mode. Th
The Stem-Cell Scandal
A group of researchers believed that subjecting tissues to trauma could give ordinary cells stem-cell-like properties.Illustration by Chad Hagen Yoshiki Sasai was known as “the brainmaker.” One of Japan’s foremost developmental biologists, he made discoveries that illuminated the formation of the embryonic nervous system, and, using stem cells, he grew the optic cup, parts of the cerebral cortex,
Summary of the Amazon EC2 and Amazon RDS Service Disruption in the US East Region
April 29, 2011 Now that we have fully restored functionality to all affected services, we would like to share more details with our customers about the events that occurred with the Amazon Elastic Compute Cloud (“EC2”) last week, our efforts to restore the services, and what we are doing to prevent this sort of issue from happening again. We are very aware that many of our customers were significa
お待ちかね Consul 0.5.0 が出ました -> https://hashicorp.com/blog/consul-0-5.html 今回のリリースでいろんな機能が追加されましたが lock が気になったのでとりあえず動かしてみます。 環境準備 Consulと使いそうなツールを幾つか含んだDockerコンテナで検証してみます。 FROM ubuntu:trusty MAINTAINER foostan ks@fstn.jp RUN apt-get update && apt-get install -y wget curl unzip telnet dnsutils RUN wget http://stedolan.github.io/jq/download/linux64/jq RUN chmod +x jq RUN mv jq /usr/bin ## consul RUN wg
システムクラスローダと似たようなものに、「(スレッドの) コンテキストクラスローダ (context class loader)」というものがある。前々から名前だけは知っていたのだが、特に必要とする機会もなかったので何なのかは知らないままだった。今回、システムクラスローダが何なのかを調べたついでにこちらも調べたので、これも忘れないように書いておく。 そのスレッドで使われるクラスローダ、ではない 時折見かける間違いとして、「スレッドのコンテキストクラスローダは、そのスレッド内で発生するクラスやリソースのロード要求を処理する」というものがある: 『クラスローダサーブレット-TECHSCORE-』 ところでアプリケーションはメインスレッドも含めて、必ず１つ「コンテクスト・クラスローダ」を持ちます。コンテキスト・クラスローダとは、そのスレッド内でクラスをロードする場合に使用されるクラスローダのこと
Getting Started Introduction A simple tutorial Language Reference Basic syntax Types Variables Constants Expressions Operators Control Structures Functions Classes and Objects Namespaces Enumerations Errors Exceptions Fibers Generators Attributes References Explained Predefined Variables Predefined Exceptions Predefined Interfaces and Classes Predefined Attributes Context options and parameters Su
J( 'ｰ`)し「たかしへ。Gitlab Merge Request Builder Pluginを入れてみたわよ」 - くりにっき
Gitlab Merge Request Builder PluginはGitlabのMergeRequest（以降MR）をビルドして結果をレスしてくれるJenkinsプラグインです Travis CIとかCircle CIのGitlab + Jenkins版 以前社内で発表したことを社内Gitlabでやりたいなぁと思って探したら見つかりました Gitlab Merge Request Builder Plugin - Jenkins - Jenkins Wiki timols/jenkins-gitlab-merge-request-builder-plugin Jenkins/Gitlab Merge Request Builder PluginのREADME訳 - 自由課題 便利そうなんだけど図入りの説明がなかったので（主に社内用に）導入方法まとめています。 forkされたリポジトリ
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Version 5.0.0 of Angular Now Available – Angular Blog
Quintus JavaScript HTML5 Game Engine
Building a JSON API with Rails 5
Document Object Model Events - 1.6.5. HTML event types
Browser-level image lazy loading for the web | Articles | web.dev
『CyberAgentでの「うるう秒」対策』
Document Object Model (DOM) - Web APIs | MDN
「ＳＴＡＰ細胞」報道 「美人だから信じる」とは… 淡々と検証を
福島第一 Fukushima ☢ Nuclear Blast?
「ウォール街占拠」運動の背後にちらつくソロス氏: 極東ブログ
さくら、「レンタルサーバ」サービスに国外IPフィルタ設定を適用へ
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CSS vs. JS Animation: Which is Faster?
2011 Tōhoku earthquake and tsunami - Wikipedia
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Game review Cool Diamonds 2 - Open Sesame Casino
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PHP: PHP 5 ChangeLog - Version 5.4.0