Here we report a unique cellular reprogramming phenomenon, called stimulus-triggered acquisition of pluripotency (STAP), which requires neither nuclear transfer nor the introduction of transcription factors. In STAP, strong external stimuli such as a transient low-pH stressor reprogrammed mammalian somatic cells, resulting in the generation of pluripotent cells. Through real-time imaging of STAP c
![(PDF) Stimulus-triggered fate conversion of somatic cells into pluripotency](https://cdn-ak-scissors.b.st-hatena.com/image/square/5207dd3160b28a96d688b2ba7721efc68c757204/height=288;version=1;width=512/https%3A%2F%2Fi1.rgstatic.net%2Fpublication%2F259984904_Stimulus-triggered_fate_conversion_of_somatic_cells_into_pluripotency%2Flinks%2F544edcd90cf2bca5ce90beeb%2Flargepreview.png)