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Researchers identify a cellular defect common to familial and sporadic forms of ALS When CHMP7 accumulates in the nucleus, certain proteins become missing from nuclear pores (outlined in white). This causes the pores to break apart, leading to downstream effects that may cause ALS.Rothstein Lab Amyotrophic lateral sclerosis (ALS) is a rapidly progressive and fatal degenerative disease affecting th
This scanning electron microscope image shows SARS-CoV-2 (yellow)—also known as 2019-nCoV, the virus that causes COVID-19—isolated from a patient in the U.S., emerging from the surface of cells (blue/pink) cultured in the lab.NIAID-RML What The virus that causes coronavirus disease 2019 (COVID-19) is stable for several hours to days in aerosols and on surfaces, according to a new study from Nation
The National Institutes of Health’s Clinical Center has made a large-scale dataset of CT images publicly available to help the scientific community improve detection accuracy of lesions. While most publicly available medical image datasets have less than a thousand lesions, this dataset, named DeepLesion, has over 32,000 annotated lesions identified on CT images. The images, which have been thorou
NIH Clinical Center provides one of the largest publicly available chest x-ray datasets to scientific community The dataset of scans is from more than 30,000 patients, including many with advanced lung disease. What The NIH Clinical Center recently released over 100,000 anonymized chest x-ray images and their corresponding data to the scientific community. The release will allow researchers across
NIH and Sanofi scientists prepare to test antibody in people. Diagram of the “three-in-one” HIV antibody. The blue, purple and green segments each bind to a different critical site on the virus. Sanofi A three-pronged antibody made in the laboratory protected monkeys from infection with two strains of SHIV, a monkey form of HIV, better than individual natural antibodies from which the engineered a
A Checklist for Communicating Science and Health Research to the Public As science and health communicators, our main goal is to share our institutions’ wealth of science and health knowledge. We strive to make the information accessible to a broad range of people—from scientists and health professionals to health educators to patients and the general public. By pooling the experience and advice f
MRI and EEG could identify children at risk for epilepsy after febrile seizures MRI scan of a child within 72 hours of febrile status epilepticus. The hippocampus on one side of the brain appears to light up (arrow, lower left), consistent with an acute injury. Republished from Shinnar et al., Neurology. WNL. 0b013e318266fcc5 Seizures during childhood fever are usually benign, but when prolonged,
NIH, Lacks family reach understanding to share genomic data of HeLa cells New NIH policy requires researchers to apply for access to the full genome sequence data from HeLa cells. Multiphoton fluorescence image of cultured HeLa cells with a fluorescent protein targeted to the Golgi apparatus (orange), microtubules (green) and counterstained for DNA (cyan). NIH-funded work at the National Center fo
NIH funds new grants exploring use of genome sequencing in patient care The National Institutes of Health has awarded four grants for up to four years to multidisciplinary research teams to explore the use of genome sequencing in medical care. The awards total approximately $6.7 million in the first year and, if funding remains available, approximately $27 million in total. The areas of research b
NIH study finds that coffee drinkers have lower risk of death Older adults who drank coffee — caffeinated or decaffeinated — had a lower risk of death overall than others who did not drink coffee, according a study by researchers from the National Cancer Institute (NCI), part of the National Institutes of Health, and AARP. Coffee drinkers were less likely to die from heart disease, respiratory dis
Scans reveal astonishingly simple 3D grid structure – NIH-funded study. The brain appears to be wired more like the checkerboard streets of New York City than the curvy lanes of Columbia, Md., suggests a new brain imaging study. The most detailed images, to date, reveal a pervasive 3D grid structure with no diagonals, say scientists funded by the National Institutes of Health. “Far from being just
Seeking Input on HIV Research Priorities NIH has issued a Request for Information to inform the next strategic plan for NIH HIV research. Learn more » Smile! World Oral Health Day is March 20th. Find out more about oral health from NIDCR. Learn more » Long COVID RECOVER Initiative opens enrollment for clinical trials evaluating treatments for symptoms such as fast heart rate, dizziness and fatigue
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