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Genome Analysis Toolkit Variant Discovery in High-Throughput Sequencing Data Need Help? Search our documentation Community Forum Hi, How can we help? Developed in the Data Sciences Platform at the Broad Institute, the toolkit offers a wide variety of tools with a primary focus on variant discovery and genotyping. Its powerful processing engine and high-performance computing features make it capabl
We are pleased to announce the release of DISCOVAR de novo, our new assembler that is suitable suitable for large genomes up to human size. DISCOVAR de novo, uses the same cheap data that the original DISCOVAR release does: 250 base paired-end PCR-free Illumina reads. No other libraries are required. For more information please visit the DISCOVAR blog, or check out the online demo.
Human MSigDB Collections The 34837 gene sets in the Human Molecular Signatures Database (MSigDB) are divided into 9 major collections, and several subcollections. See the table below for a brief description of each, and the Human MSigDB Collections: Details and Acknowledgments page for more detailed descriptions. See also the latest MSigDB Release Notes. Click on the "browse gene sets" links in th
Overview Gene Set Enrichment Analysis (GSEA) is a computational method that determines whether an a priori defined set of genes shows statistically significant, concordant differences between two biological states (e.g. phenotypes). Download the GSEA software and additional resources to analyze, annotate and interpret enrichment results. Explore the Molecular Signatures Database (MSigDB), a collec
Features Powerful genomics tools in a user-friendly interface GenePattern provides hundreds of analytical tools for the analysis of gene expression (RNA-seq and microarray), sequence variation and copy number, proteomic, flow cytometry, and network analysis. These tools are all available through a Web interface with no programming experience required. GenePattern Notebook The GenePattern Notebook
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